1265916-41-3
1265916-41-3
Chemical Structure
BIX02189
- CAS No.: 1265916-41-3
- Formula:C27H28N4O2
- Molecular Weight:440.55
IUPAC Name: (Z)-3-(((3-((dimethylamino)methyl)phenyl)amino)(phenyl)methylene)-N,N-dimethyl-2-oxoindoline-6-carboxamide
InChIKey: HOMJAAIVTDVQJA-IZHYLOQSSA-N
SMILES: O=C(N(C)C)C1=CC(NC2=O)=C(/C2=C(C3=CC=CC=C3)/NC4=CC=CC(CN(C)C)=C4)C=C1
Biological Activity: BIX02189 is a potent and selective MEK5 inhibitor with an IC50 of 1.5 nM. BIX02189 also inhibits ERK5 catalytic activity with an IC50 of 59 nM.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
BIX02189 | 99.72% | BIX02189 is a potent and selective MEK5 inhibitor with an IC50 of 1.5 nM. BIX02189 also inhibits ERK5 catalytic activity with an IC50 of 59 nM. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Structural Analogs
-
Similarity Score 1.00
HY-12056A(E/Z)-BIX02189 -
Similarity Score 0.91
HY-12202MEK inhibitor -
Similarity Score 0.90
HY-107622(E/Z)-BIX02188 -
Similarity Score 0.90
HY-12055BIX02188 -
Similarity Score 0.80
HY-171878BI-4659 -
Similarity Score 0.72
HY-13783BIBF0775 -
Similarity Score 0.72
HY-Z0013RNintedanib impurity 7 (Standard) -
Similarity Score 0.72
HY-18955BI-847325 -
Similarity Score 0.71
HY-Z4752Nintedanib impurity 3 -
Explore the MedChemAI to find more analogs
