(E/Z)-BIX02189
(E/Z)-BIX02189 is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- CAS. Nr.: 1094614-85-3
- Formel: C27H28N4O2
- Molecular Weight:440.54
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
- Reinheit & Dokumentation
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Help & FAQs
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Biologische Aktivität
Beschreibung
Cellular Effect
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Cell Line
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Type | Value | Description | References |
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| HeLa | IC50 |
59 nM
Compound: BIX02189
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Inhibition of ERK5 phosphorylation in sorbitol-stimulated human HeLa cells
Inhibition of ERK5 phosphorylation in sorbitol-stimulated human HeLa cells
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[PMID: 23656407] |
In Vitro
BIX 02189 is a selective MEK5 inhibitor with IC50 of 1.5 nM, also inhibits the catalytic activity of ERK5 with IC50 of 810 nM, without inhibiting its closely related kinases MEK1, MEK2, ERK2, and JNK2.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
Chemical Information
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CAS. Nr. 1094614-85-3
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Molecular Weight 440.54
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Formel C27H28N4O2
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SMILES
O=C(N(C)C)C1=CC(NC2=O)=C(/C2=C(C3=CC=CC=C3)/NC4=CC=CC(CN(C)C)=C4)C=C1
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
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Data Sheet (244 KB)
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SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
(E/Z)-BIX02189 Related Classifications
HY-12056A Related Classifications
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