1269815-17-9
1269815-17-9
Chemical Structure
CDK-IN-2
Synonym(s): CDK inhibitor II
- CAS No.: 1269815-17-9
- Formula:C18H19ClFN3O2
- Molecular Weight:363.81
IUPAC Name: (R)-N-(5-chloro-4-(5-fluoro-2-methoxyphenyl)pyridin-2-yl)piperidine-3-carboxamide
InChIKey: AHMKHNVZGOQLRQ-LLVKDONJSA-N
SMILES: FC1=CC(C2=CC(NC([C@H]3CNCCC3)=O)=NC=C2Cl)=C(C=C1)OC
Biological Activity: CDK-IN-2 is a specific CDK9 inhibitor with an IC50 of less than 8 nM. CDK-IN-2 reduces the phosphorylation level of H3S10. CDK-IN-2 decreases the transition rate of spermatocytes from prophase to metaphase I[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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CDK-IN-2 | 99.27% | CDK-IN-2 is a specific CDK9 inhibitor with an IC50 of less than 8 nM. CDK-IN-2 reduces the phosphorylation level of H3S10. CDK-IN-2 decreases the transition rate of spermatocytes from prophase to metaphase I. | ||||||||||||||||||||
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References
Keywords
