128-68-7
128-68-7
Chemical Structure
Phenicin
Synonym(s): Phoenicine
- No. CAS: 128-68-7
- Formula:C14H10O6
- Molecular Weight:274.23
InChIKey: BFRRTQSWBORPKV-UHFFFAOYSA-N
SMILES: O=C1C=C(C)C(C(O)=C1C(C(C=C2C)=O)=C(O)C2=O)=O
Biological Activity: Phenicin (Phoenicine), a microbial metabolite, is an irreversible HMG-CoA reductase (HMGCR) inhibitor. Phenicin can be isolated from cultures of Penicillium phoeniceum and Penicillium rubrum. Phenicin specifically inhibits the conversion of HMG-CoA to mevalonate catalyzed by HMGCR, effectively inhibiting cholesterol synthesis[1].
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Phenicin | Phenicin (Phoenicine), a microbial metabolite, is an irreversible HMG-CoA reductase (HMGCR) inhibitor. Phenicin can be isolated from cultures of Penicillium phoeniceum and Penicillium rubrum. Phenicin specifically inhibits the conversion of HMG-CoA to mevalonate catalyzed by HMGCR, effectively inhibiting cholesterol synthesis. | |||||||||||||||||||||
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