130-16-5
130-16-5
Chemical Structure
Cloxiquine
Synonym(s): 5-Chloro-8-quinolinol
- CAS No.: 130-16-5
- Formula:C9H6ClNO
- Molecular Weight:179.60
IUPAC Name: 5-chloroquinolin-8-ol
InChIKey: CTQMJYWDVABFRZ-UHFFFAOYSA-N
SMILES: OC1=C2N=CC=CC2=C(Cl)C=C1
Biological Activity: Cloxiquine (5-Chloro-8-quinolinol) is an antibacterial, antifungal and antiamoebic agent. Cloxiquine can be used for the research of tuberculosis and dermatoses. Cloxiquine suppresses the growth and metastasis of melanoma cells through activation of PPARγ[1][2].
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Cloxiquine | 99.94% | Cloxiquine (5-Chloro-8-quinolinol) is an antibacterial, antifungal and antiamoebic agent. Cloxiquine can be used for the research of tuberculosis and dermatoses. Cloxiquine suppresses the growth and metastasis of melanoma cells through activation of PPARγ. | ||||||||||||||||||||
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Cloxiquine (Standard) | ≥98% | Cloxiquine (Standard) is the analytical standard of Cloxiquine. This product is intended for research and analytical applications. Cloxiquine (5-Chloro-8-quinolinol) is an antibacterial, antifungal and antiamoebic agent. Cloxiquine can be used for the research of tuberculosis and dermatoses. Cloxiquine suppresses the growth and metastasis of melanoma cells through activation of PPARγ. | ||||||||||||||||||||
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References
- [1]. Latosińska JN, et al. Supramolecular synthon pattern in solid clioquinol and cloxiquine (APIs of antibacterial, antifungal, antiaging and antituberculosis drugs) studied by 35Cl NQR, 1H-17O and 1H-14N NQDR and DFT/QTAIM. J Mol Model. 2011 Jul;17(7):1781-800. [Content Brief]
- [2]. Zhang W, et, al. Cloxiquine, a traditional antituberculosis agent, suppresses the growth and metastasis of melanoma cells through activation of PPARγ. Cell Death Dis. 2019 May 28;10(6):404. [Content Brief]
Keywords
