13484-66-7

IST5-002 Chemical Structure
13484-66-7

Chemical Structure

IST5-002

Synonym(s): N6-Benzyladenosine-5'-phosphate

  • CAS No.: 13484-66-7
  • Formula:C17H20N5O7P
  • Molecular Weight:437.34

IUPAC Name: ((2R,3S,4R,5R)-5-(6-(benzylamino)-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl dihydrogen phosphate

InChIKey: DWVANBHPEPSMOV-LSCFUAHRSA-N

SMILES: O=P(O)(OC[C@@H]1[C@H]([C@H]([C@H](N2C=NC3=C(N=CN=C32)NCC4=CC=CC=C4)O1)O)O)O

Biological Activity: IST5-002, a potent Stat5a/b inhibitor, selectively inhibits transcriptional activity of Stat5a/b (IC50s: 1.5 μM for Stat5a, 3.5 μM for Stat5b). IST5-002 inducs cell apoptotic and death of prostate cancer cells and chronic myeloid leukemia (CML) cells. IST5-002 can be used in the research of prostate cancer and chronic myeloid leukemia (CML)[1].

Cat. No. Product Name Purity Description Pricing
HY-19527
IST5-002 99.83% IST5-002, a potent Stat5a/b inhibitor, selectively inhibits transcriptional activity of Stat5a/b (IC50s: 1.5 μM for Stat5a, 3.5 μM for Stat5b). IST5-002 inducs cell apoptotic and death of prostate cancer cells and chronic myeloid leukemia (CML) cells. IST5-002 can be used in the research of prostate cancer and chronic myeloid leukemia (CML).
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