135503-67-2
135503-67-2
Chemical Structure
LY 254155
- CAS No.: 135503-67-2
- Formula:C19H23N5O6S
- Molecular Weight:449.48
IUPAC Name: (5-(2-(2-amino-4-oxo-3,4,5,6,7,8-hexahydropyrido[2,3-d]pyrimidin-6-yl)ethyl)thiophene-2-carbonyl)-L-glutamic acid
InChIKey: GQCXGHHHNACOGE-ACGXKRRESA-N
SMILES: O=C1C2=C(NCC(CCC(S3)=CC=C3C(N[C@@H](CCC(O)=O)C(O)=O)=O)C2)N=C(N)N1
Biological Activity: LY 254155, an antifolate, inhibits hGARFT and binds to mFBP with Kis of 2.1±0.2 and 1.7±0.1 nM, respectively.
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LY 254155 | LY 254155, an antifolate, inhibits hGARFT and binds to mFBP with Kis of 2.1±0.2 and 1.7±0.1 nM, respectively. | |||||||||||||||||||||
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Keywords
