13571-44-3
13571-44-3
Chemical Structure
VPC-70063
- CAS No.: 13571-44-3
- Formula:C16H12F6N2S
- Molecular Weight:378.34
IUPAC Name: 1-benzyl-3-(3,5-bis(trifluoromethyl)phenyl)thiourea
InChIKey: PIQMVCPITQIXGJ-UHFFFAOYSA-N
SMILES: FC(F)(C1=CC(NC(NCC2=CC=CC=C2)=S)=CC(C(F)(F)F)=C1)F
Biological Activity: VPC-70063 is a potent Myc-Max inhibitor with an IC50 value of 8.9 μM for Myc-Max transcriptional activity inhibition. VPC-70063 reduces UBE2C promotor activity and AR-V7 levels, and induces PARP cleavage. VPC-70063 induces apoptosis and blocks Myc-Max interactions with DNA. VPC-70063 can be used for researching anticancer[1].
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VPC-70063 | 99.92% | VPC-70063 is a potent Myc-Max inhibitor with an IC50 value of 8.9 μM for Myc-Max transcriptional activity inhibition. VPC-70063 reduces UBE2C promotor activity and AR-V7 levels, and induces PARP cleavage. VPC-70063 induces apoptosis and blocks Myc-Max interactions with DNA. VPC-70063 can be used for researching anticancer. | ||||||||||||||||||||
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References
Keywords
