13571-44-3
13571-44-3
Chemical Structure
VPC-70063
- CAS No.: 13571-44-3
- Formula:C16H12F6N2S
- Molecular Weight:378.34
IUPAC Name: 1-benzyl-3-(3,5-bis(trifluoromethyl)phenyl)thiourea
InChIKey: PIQMVCPITQIXGJ-UHFFFAOYSA-N
SMILES: FC(F)(C1=CC(NC(NCC2=CC=CC=C2)=S)=CC(C(F)(F)F)=C1)F
Biological Activity: VPC-70063 is a potent Myc-Max inhibitor with an IC50 value of 8.9 μM for Myc-Max transcriptional activity inhibition. VPC-70063 reduces UBE2C promotor activity and AR-V7 levels, and induces PARP cleavage. VPC-70063 induces apoptosis and blocks Myc-Max interactions with DNA. VPC-70063 can be used for researching anticancer[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
VPC-70063 | 99.91% | VPC-70063 is a potent Myc-Max inhibitor with an IC50 value of 8.9 μM for Myc-Max transcriptional activity inhibition. VPC-70063 reduces UBE2C promotor activity and AR-V7 levels, and induces PARP cleavage. VPC-70063 induces apoptosis and blocks Myc-Max interactions with DNA. VPC-70063 can be used for researching anticancer. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Structural Analogs
-
Similarity Score 0.68
HY-178189Laccase-IN-6 -
Similarity Score 0.63
HY-W1119991-Benzyl-3-phenylthiourea -
Similarity Score 0.62
HY-163940LX1 -
Similarity Score 0.62
HY-W131444Insecticidal agent 15 -
Similarity Score 0.61
HY-10172RIMD-0354 (Standard) -
Similarity Score 0.61
HY-144737Anti-inflammatory agent 15 -
Similarity Score 0.61
HY-152094SRD5A1-IN-1 -
Similarity Score 0.61
HY-151356Antibacterial agent 122 -
Similarity Score 0.60
HY-180511MurA-IN-7 -
Explore the MedChemAI to find more analogs
