136609-26-2
136609-26-2
Chemical Structure
RP 70676
- CAS No.: 136609-26-2
- Formula:C25H28N4S
- Molecular Weight:416.58
IUPAC Name: 1-(5-((4,5-diphenyl-1H-imidazol-2-yl)thio)pentyl)-3,5-dimethyl-1H-pyrazole
InChIKey: UUPITLNVYVCTFW-UHFFFAOYSA-N
SMILES: CC1=CC(C)=NN1CCCCCSC2=NC(C3=CC=CC=C3)=C(C4=CC=CC=C4)N2
Biological Activity: RP 70676 is a potent inhibitor of ACAT, with IC50 of 25 and 44 nM for rat and rabbit ACAT.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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RP 70676 | 99.22% | RP 70676 is a potent inhibitor of ACAT, with IC50 of 25 and 44 nM for rat and rabbit ACAT. | ||||||||||||||||||||
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RP 70676 (Standard) | ≥98% | RP 70676 (Standard) is the analytical standard of RP 70676 (HY-101576). This product is intended for research and analytical applications. RP 70676 is a potent inhibitor of ACAT, with IC50 of 25 and 44 nM for rat and rabbit ACAT. | ||||||||||||||||||||
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RP 73163 Racemate | RP 73163 Racemate is the racemate of RP 73163. RP 73163 is a potent ACAT inhibitor, with cholesterol lowering activity. | |||||||||||||||||||||
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I-XW-053 | 99.71% | I-XW-053 is a specific anti-HIV-1 capsid inhibitor (IC50=164.2 μM). By binding to the CA NTD-NTD hexamerization interface and the R173 region of CTD (Kd=66.3 μM), I-XW-053 disrupts capsid function and reduces polymerization levels. I-XW-053 effectively blocks HIV-1 uncoating, inhibits reverse transcription and early replication, and exhibits broad-spectrum activity against primary HIV-1 isolates in peripheral blood mononuclear cells. I-XW-053 can be widely used in studies related to HIV-1 infection. | ||||||||||||||||||||
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I-XW-053 sodium | I-XW-053 sodium is a specific anti-HIV-1 capsid inhibitor (IC50=164.2 μM). By binding to the CA NTD-NTD hexamerization interface and the R173 region of CTD (Kd=66.3 μM), I-XW-053 sodium disrupts capsid function and reduces polymerization levels. I-XW-053 sodium effectively blocks HIV-1 uncoating, inhibits reverse transcription and early replication, and exhibits broad-spectrum activity against primary HIV-1 isolates in peripheral blood mononuclear cells. I-XW-053 sodium can be widely used in studies related to HIV-1 infection. | |||||||||||||||||||||
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Trifenagrel (Standard) | ≥98% | Trifenagrel (Standard) is the analytical standard of Trifenagrel (HY-105872). This product is intended for research and analytical applications. Trifenagrel is an orally active platelet aggregation inhibitor that inhibits the inducing effects of arachidonic acid (AA) and collagen. The ED50s of trifenagrel for inhibiting AA- and collagen-induced platelet aggregation in guinea pigs were 1.4 mg/kg and 9.4 mg/kg, respectively. | ||||||||||||||||||||
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Lecimibide | 99.54% | Lecimibide (DuP 128) is a potent and specific acyl-CoA:cholesterol acyltransferase (ACAT) inhibitor for antihyperlipidemia research. | ||||||||||||||||||||
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HDAC6-IN-82 | HDAC6-IN-82 is a selective HDAC6 inhibitor with an IC50 of 4.9 nM against HDAC6. HDAC6-IN-82 inhibits HDAC1 (112 nM), HDAC2 (737 nM), HDAC3 (623 nM), HDAC8 (1140 nM), HDAC10 (91.4 nM) and HDAC11 (219 nM). HDAC6-IN-82 reduces cancer cell viability, induces cell cycle arrest, triggers apoptosis, and increases the acetylation levels of H3K9 and α-tubulin. HDAC6-IN-82 can be used in cancer-related research such as leukemia. | |||||||||||||||||||||
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4-(4,5-Diphenyl-1H-imidazol-2-yl)benzoyl chloride | 98.0% | 4-(4,5-Diphenyl-1H-imidazol-2-yl)benzoyl chloride (DIB-Cl) is a fluorescent labeling reagent. 4-(4,5-Diphenyl-1H-imidazol-2-yl)benzoyl chloride can be used for labeling amines and successfully being applied to determine activator amines by HPLC. | ||||||||||||||||||||
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4-(4,5-Diphenyl-1H-imidazol-2-yl)phenol | 4-(4,5-Diphenyl-1H-imidazol-2-yl)phenol is an organic compound commonly used in fluorescent dyes and catalysts. It can be used to prepare some organic light-emitting diodes (OLEDs) and organic solar cells, and is widely used in chemical sensors and analytical instruments. In addition, this compound is used as a catalyst or buffer in certain chemical reactions. | |||||||||||||||||||||
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Lophine | 99.03% | Lophine is a traditional chemiluminescent and fluorescent probe. Lophine and its derivatives are widely applied for reactive oxygen species (ROS) detection. | ||||||||||||||||||||
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4-(4,5-Diphenyl-1H-imidazol-2-yl)pyridine | 4-(4,5-Diphenyl-1H-imidazol-2-yl)pyridine is a metal-organic framework (MOF). | |||||||||||||||||||||
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