1375465-91-0
Chemical Structure
ACY-738
- CAS No.: 1375465-91-0
- Formula:C14H14N4O2
- Molecular Weight:270.29
IUPAC Name: N-hydroxy-2-((1-phenylcyclopropyl)amino)pyrimidine-5-carboxamide
InChIKey: LIIWIMDSZVNYHY-UHFFFAOYSA-N
SMILES: O=C(NO)C(C=N1)=CN=C1NC2(CC2)C3=CC=CC=C3
Biological Activity: ACY-738 is a potent, selective and orally-bioavailable HDAC6 inhibitor, with an IC50 of 1.7 nM; ACY-738 also inhibits HDAC1, HDAC2, and HDAC3, with IC50s of 94, 128, and 218 nM.
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ACY-738 | 99.92% | ACY-738 is a potent, selective and orally-bioavailable HDAC6 inhibitor, with an IC50 of 1.7 nM; ACY-738 also inhibits HDAC1, HDAC2, and HDAC3, with IC50s of 94, 128, and 218 nM. | ||||||||||||||||||||
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Keywords