1401033-86-0
1401033-86-0
Chemical Structure
AMG 925
- CAS No.: 1401033-86-0
- Formula:C26H29N7O2
- Molecular Weight:471.55
IUPAC Name: 2-hydroxy-1-(2-((9-((1r,4r)-4-methylcyclohexyl)-9H-pyrido[4',3':4,5]pyrrolo[2,3-d]pyrimidin-2-yl)amino)-7,8-dihydro-1,6-naphthyridin-6(5H)-yl)ethan-1-one
InChIKey: BBUVDDPUURMFOX-SAABIXHNSA-N
SMILES: OCC(N1CC2=C(N=C(NC3=NC=C4C(N([C@H]5CC[C@H](C)CC5)C6=CN=CC=C64)=N3)C=C2)CC1)=O
Biological Activity: AMG 925 is a potent, selective, and orally available FLT3/CDK4 dual inhibitor with IC50s of 2±1 nM and 3±1 nM, respectively.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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AMG 925 | 98.71% | AMG 925 is a potent, selective, and orally available FLT3/CDK4 dual inhibitor with IC50s of 2±1 nM and 3±1 nM, respectively. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.99
HY-15889AAMG 925 (HCl) -
Similarity Score 0.57
HY-153088CDK4/6-IN-16 -
Similarity Score 0.52
HY-164376CDK4/6-IN-21 -
Similarity Score 0.51
HY-114338ADalpiciclib hydrochloride -
Similarity Score 0.51
HY-114338Dalpiciclib -
Similarity Score 0.51
HY-164376ACDK4/6-IN-21 maleate -
Similarity Score 0.50
HY-50767Palbociclib -
Similarity Score 0.50
HY-131466N-Methyl Palbociclib -
Similarity Score 0.50
HY-50767APalbociclib monohydrochloride -
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