N-Methyl Palbociclib
Based on 1 Customer Validation
N-Methyl Palbociclib is an impurity of Palbociclib (HY-50767). Palbociclib (PD 0332991) is an orally active selective CDK4 and CDK6 inhibitor.
For research use only. We do not sell to patients.
- Purity: 99.94%
- CAS No.: 571189-51-0
- Formula: C25H31N7O2
- Molecular Weight:461.56
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| MDA-MB-435 | IC50 |
0.325 μM
Compound: 55(table4)
|
Inhibitory concentration was measured by the incorporation of [14C]-thymidine in (human breast carcinoma) MDA-MB-435 cell line
Inhibitory concentration was measured by the incorporation of [14C]-thymidine in (human breast carcinoma) MDA-MB-435 cell line
|
[PMID: 15801831] |
Chemical Information
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CAS No. 571189-51-0
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Appearance Solid
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Molecular Weight 461.56
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Formula C25H31N7O2
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Color Light yellow to yellow
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SMILES
O=C1C(C(C)=O)=C(C)C2=CN=C(NC3=NC=C(N4CCN(C)CC4)C=C3)N=C2N1C5CCCC5
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : < 1 mg/mL (insoluble or slightly soluble)
Purity & Documentation
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Data Sheet (241 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)