140853-10-7

(DHQD)2PHAL Chemical Structure
140853-10-7

Chemical Structure

(DHQD)2PHAL

Synonym(s): C-61; SYKINH-61

  • CAS No.: 140853-10-7
  • Formula:C48H54N6O4
  • Molecular Weight:778.98

IUPAC Name: 1-((1S)-((2R,4S,5R)-5-ethylquinuclidin-2-yl)(6-methoxyquinolin-4-yl)methoxy)-4-((S)-((1R,2R,4S,5R)-5-ethylquinuclidin-2-yl)(6-methoxyquinolin-4-yl)methoxy)phthalazine

InChIKey: YUCBLVFHJWOYDN-HVLQGHBFSA-N

SMILES: CC[C@H]1C[N@]2[C@@](C[C@]1([H])CC2)([H])[C@H](C3=CC=NC(C=C4)=C3C=C4OC)OC(C5=C6C=CC=C5)=NN=C6O[C@@H](C7=CC=NC(C=C8)=C7C=C8OC)[C@](C[C@]9([H])CC%10)([H])N%10C[C@@H]9CC

Biological Activity: (DHQD)2PHAL (C-61) is a SYK tyrosine kinase inhibitor. (DHQD)2PHAL blocks SYK-dependent STAT3 signaling and prevents oxidative stress-induced STAT3 tyrosine phosphorylation and DNA-binding activity. (DHQD)2PHAL promotes oxidative stress-induced apoptosis. (DHQD)2PHAL can be used in research on B-cell precursor leukemia and B-lineage acute lymphoblastic leukemia[1][2][3].

Cat. No. Product Name Purity Description Pricing
HY-W008033 		(DHQD)2PHAL 98.0% (DHQD)2PHAL (C-61) is a SYK tyrosine kinase inhibitor. (DHQD)2PHAL blocks SYK-dependent STAT3 signaling and prevents oxidative stress-induced STAT3 tyrosine phosphorylation and DNA-binding activity. (DHQD)2PHAL promotes oxidative stress-induced apoptosis. (DHQD)2PHAL can be used in research on B-cell precursor leukemia and B-lineage acute lymphoblastic leukemia.
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This product is a controlled substance and not for sale in your territory.

This product is not for sale in your territory.

This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

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Keywords