14208-10-7
14208-10-7
Chemical Structure
p-Xylene bispyridinium bromide
- CAS No.: 14208-10-7
- Formula:C18H18Br2N2
- Molecular Weight:422.16
IUPAC Name: 1,1'-(1,4-phenylenebis(methylene))bis(pyridin-1-ium) bromide
InChIKey: MMKBQSJLLGHVIM-UHFFFAOYSA-L
SMILES: C1=CC=[N+](C=C1)CC2=CC=C(C=C2)C[N+]3=CC=CC=C3.[Br-].[Br-]
Biological Activity: p-Xylene bis(pyridinium bromide) (compound 21), a cationic charged quencher, is a week bisquaternary AChE and BChE inhibitor with IC50s of 1540 μM and 529 μM, respectively[1][2].
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p-Xylene bispyridinium bromide | 99.60% | p-Xylene bis(pyridinium bromide) (compound 21), a cationic charged quencher, is a week bisquaternary AChE and BChE inhibitor with IC50s of 1540 μM and 529 μM, respectively. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.66
HY-W1650851,10-Bis(pyridinium)decane -
Similarity Score 0.66
![Pyridinium, 1,1′-[1,4-phenylenebis(methylene)]bis[4-carboxy-, bromide (1:2) Chemical Structure](//file.medchemexpress.com/product_pic/hy-w586865.gif)
HY-W586865Pyridinium, 1,1′-[1,4-phenylenebis(methylene)]bis[4-carboxy-, bromide (1:2) -
Similarity Score 0.64
HY-W4563651,1'-(1,4-Phenylenebis(methylene))bis(4-carboxypyridin-1-ium) chloride -
Similarity Score 0.64
HY-183750BChE reactivator-1 -
Similarity Score 0.64
HY-W0748611,4-Bis((1H-imidazol-1-yl)methyl)benzene -
Similarity Score 0.63
HY-129583Lepidiline A -
Similarity Score 0.63
HY-W4565634-Carboxy-1-(4-carboxybenzyl)pyridin-1-ium bromide -
Similarity Score 0.62
HY-W7925621,4-Bis(pyridin-4-ylmethyl)benzene -
Similarity Score 0.62
HY-W1127561,4-Bis((4H-1,2,4-triazol-4-yl)methyl)benzene -
Explore the MedChemAI to find more analogs
![Pyridinium, 1,1′-[1,4-phenylenebis(methylene)]bis[4-carboxy-, bromide (1:2) Chemical Structure](http://file.medchemexpress.com/product_pic/hy-w586865.gif)
References
- [1]. M Smolarsky, et al. A simple fluorescent method to determine complement-mediated liposome immune lysis. J Immunol Methods. 1977;15(3):255-65. [Content Brief]
- [2]. Kamil Musilek, et al. Preparation and in vitro screening of symmetrical bispyridinium cholinesterase inhibitors bearing different connecting linkage-initial study for Myasthenia gravis implications. Bioorg Med Chem Lett. 2010 Mar 1;20(5):1763-6. [Content Brief]
