1421372-66-8
1421372-66-8
Chemical Structure
Mutated EGFR-IN-1
Synonym(s): Osimertinib analog
- CAS No.: 1421372-66-8
- Formula:C25H31N7O
- Molecular Weight:445.56
IUPAC Name: N1-(2-(dimethylamino)ethyl)-5-methoxy-N1-methyl-N4-(4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl)benzene-1,2,4-triamine
InChIKey: HTNTZPBKKCORTP-UHFFFAOYSA-N
SMILES: NC1=CC(NC2=NC=CC(C3=CN(C)C4=C3C=CC=C4)=N2)=C(OC)C=C1N(CCN(C)C)C
Biological Activity: Mutated EGFR-IN-1 (Osimertinib analog) (Intermediate 168) is a structural analog of Osimertinib (HY-15772) and can be used as a pharmaceutical intermediate for EGFR inhibitors[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Mutated EGFR-IN-1 | 99.90% | Mutated EGFR-IN-1 (Osimertinib analog) (Intermediate 168) is a structural analog of Osimertinib (HY-15772) and can be used as a pharmaceutical intermediate for EGFR inhibitors. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.85
HY-148053Rezivertinib analogue 1 -
Similarity Score 0.83
HY-15772GOsimertinib (GMP) -
Similarity Score 0.79
HY-15772AOsimertinib mesylate -
Similarity Score 0.77
HY-B0794AZ7550 -
Similarity Score 0.77
HY-B0794AAZ7550 hydrochloride -
Similarity Score 0.77
HY-153605EGFR-IN-77 -
Similarity Score 0.76
HY-79077ROsimertinib dimesylate (Standard) -
Similarity Score 0.75
HY-15772S1Osimertinib-13C,d3 -
Similarity Score 0.74
HY-147862EGFR-IN-62 -
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