1435934-53-4
1435934-53-4
Chemical Structure
DBCO-CONH-S-S-NHS ester
- CAS No.: 1435934-53-4
- Formula:C28H27N3O6S2
- Molecular Weight:565.66
InChIKey: RPNGUSKTYYIUDE-UHFFFAOYSA-N
SMILES: O=C(N1C2=CC=CC=C2C#CC3=CC=CC=C3C1)CCC(NCCSSCCC(ON4C(CCC4=O)=O)=O)=O
Biological Activity: DBCO-CONH-S-S-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. DBCO-CONH-S-S-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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DBCO-CONH-S-S-NHS ester | 98.18% | DBCO-CONH-S-S-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). DBCO-CONH-S-S-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.91
HY-133412DBCO-NHCO-S-S-NHS ester -
Similarity Score 0.85
HY-140271DBCO-PEG1-NHS ester -
Similarity Score 0.82
HY-151827DBCO-PEG2-NHS ester -
Similarity Score 0.82
HY-133371DBCO-NHCO-C4-NHS ester -
Similarity Score 0.79
HY-42973DBCO-NHS ester -
Similarity Score 0.79
HY-138506DBCO-S-S-acid -
Similarity Score 0.78
HY-115524DBCO-NHS ester 2 -
Similarity Score 0.78
HY-115545DBCO-NHS ester 3 -
Similarity Score 0.78
HY-170528DBCO-PEG3-NHS -
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