1449-05-4
Chemical Structure
18α-Glycyrrhetinic acid
- CAS No.: 1449-05-4
- Formula:C30H46O4
- Molecular Weight:470.68
IUPAC Name: (2S,4aS,6aS,6bR,8aR,10S,12aS,12bR,14bS)-10-hydroxy-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-2-carboxylic acid
InChIKey: MPDGHEJMBKOTSU-PMTKVOBESA-N
SMILES: CC1(C)[C@@H](O)CC[C@@]2(C)[C@@]1([H])CC[C@]([C@@](CC[C@]3(C)[C@]4([H])C[C@@](C)(C(O)=O)CC3)(C)C4=C5)(C)[C@]2([H])C5=O
Biological Activity: 18α-Glycyrrhetinic acid, a diet-derived compound, is an inhibitor of NF-kB and an activator of proteasome, which serves as pro-longevity and anti-aggregation factor in a multicellular organism. 18α-Glycyrrhetinic acid induces apoptosis[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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18α-Glycyrrhetinic acid | 99.87% | 18α-Glycyrrhetinic acid, a diet-derived compound, is an inhibitor of NF-kB and an activator of proteasome, which serves as pro-longevity and anti-aggregation factor in a multicellular organism. 18α-Glycyrrhetinic acid induces apoptosis. | ||||||||||||||||||||
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18α-Glycyrrhetinic acid (Standard) | ≥98% | 18α-Glycyrrhetinic acid (Standard) is the analytical standard of 18α-Glycyrrhetinic acid. This product is intended for research and analytical applications. 18α-Glycyrrhetinic acid, a diet-derived compound, is an inhibitor of NF-kB and an activator of proteasome, which serves as pro-longevity and anti-aggregation factor in a multicellular organism. 18α-Glycyrrhetinic acid induces apoptosis. | ||||||||||||||||||||
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Similarity Score 1.00
HY-N018018β-Glycyrrhetinic acid -
Similarity Score 1.00
HY-N0375A3-epi-18β-Glycyrrhetinic acid -
Similarity Score 0.91
HY-W755367Methyl glycyrrhetinate -
Similarity Score 0.86
HY-N175093β-Hydroxy-oleana-11,13(18)-dien-28-oic acid -
Similarity Score 0.85
HY-N2920β-Amyrenonol -
Similarity Score 0.83
HY-169739DG 381B -
Similarity Score 0.83
HY-N1826Epikatonic acid -
Similarity Score 0.79
HY-N12162Obtusilin -
Similarity Score 0.79
HY-B1588Carbenoxolone -
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References
- [1]. Zong L et al. 18α-glycyrrhetinic acid extracted from Glycyrrhiza radix inhibits proliferation and promotes apoptosis of the hepatic stellate cell line. J Dig Dis. 2013 Jun;14(6):328-36. [Content Brief]
- [2]. Papaevgeniou N, et al. 18α-Glycyrrhetinic Acid Proteasome Activator Decelerates Aging and Alzheimer's Disease Progression in Caenorhabditis elegans and Neuronal Cultures. Antioxid Redox Signal. 2016 Dec 1;25(16):855-869. [Content Brief]
