1449236-96-7
1449236-96-7
Chemical Structure
NMS-859
- No. CAS: 1449236-96-7
- Formula:C15H12ClN3O3S
- Molecular Weight:349.79
IUPAC Name: 2-chloro-N-(3-((1,1-dioxidobenzo[d]isothiazol-3-yl)amino)phenyl)acetamide
InChIKey: JWMFLBAPPIWNGG-UHFFFAOYSA-N
SMILES: O=S1(C2=CC=CC=C2C(NC3=CC(NC(CCl)=O)=CC=C3)=N1)=O
Biological Activity: NMS-859 is a potent, covalent VCP (p97) inhibitor, with IC50s of 0.37 and 0.36 μM for wild-type VCP in the presence of 60 μM and 1 mM ATP in cells, respectively.
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NMS-859 | 98.02% | NMS-859 is a potent, covalent VCP (p97) inhibitor, with IC50s of 0.37 and 0.36 μM for wild-type VCP in the presence of 60 μM and 1 mM ATP in cells, respectively. | ||||||||||||||||||||
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Keywords
