145301-48-0
145301-48-0
Chemical Structure
BIBN-99
- CAS No.: 145301-48-0
- Formula:C31H42ClN5O3
- Molecular Weight:568.15
IUPAC Name: N-(3-(1-(2-(8-chloro-6-oxo-5,6-dihydro-11H-benzo[e]pyrido[3,2-b][1,4]diazepin-11-yl)-2-oxoethyl)piperidin-4-yl)propyl)-N-ethyl-2,2-dimethylpentanamide
InChIKey: LUPAFPUKESJDMZ-UHFFFAOYSA-N
SMILES: CCCC(C)(C(N(CC)CCCC1CCN(CC1)CC(N2C3=NC=CC=C3NC(C4=CC(Cl)=CC=C42)=O)=O)=O)C
Biological Activity: BIBN-99 is a selective, BBB-penetrable and competitive muscarinic M2 receptor antagonist. BIBN-99 improves cognitive performancein rats with traumatic brain injury[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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BIBN-99 | 98.02% | BIBN-99 is a selective, BBB-penetrable and competitive muscarinic M2 receptor antagonist. BIBN-99 improves cognitive performancein rats with traumatic brain injury. | ||||||||||||||||||||
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References
- [1]. Doods H, et al. Characterization of BIBN 99: a lipophilic and selective muscarinic M2 receptor antagonist. Eur J Pharmacol. 1993 Sep 21;242(1):23-30. [Content Brief]
- [2]. Pike BR, et al. Post-injury administration of BIBN 99, a selective muscarinic M2 receptor antagonist, improves cognitive performance following traumatic brain injury in rats. Brain Res. 1995 Jul 17;686(1):37-43. [Content Brief]
Keywords
