1453028-33-5
Chemical Structure
DRP1i27
- CAS No.: 1453028-33-5
- Formula:C20H26N6O
- Molecular Weight:366.46
IUPAC Name: (1S,5R)-6-((5-(1H-pyrazol-3-yl)furan-2-yl)methyl)-3-((4-methyl-1H-imidazol-5-yl)methyl)-3,6-diazabicyclo[3.2.2]nonane
InChIKey: PJYHAZFCIWUKAT-JKSUJKDBSA-N
SMILES: CC1=C(NC=N1)CN2C[C@@H]3CC[C@@H](N(C3)CC4=CC=C(O4)C5=NNC=C5)C2
Biological Activity: DRP1i27 is a potent inhibitor of human Drp1 (dynamin-related protein 1). DRP1i27 binds to the GTPase site of Drp1, with hydrogen bonds to Gln34 and Asp218. DRP1i27 targets Drp1-mediated mitochondrial fission in cell line models and protects against simulated ischemia-reperfusion injury[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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DRP1i27 | 99.36% | DRP1i27 is a potent inhibitor of human Drp1 (dynamin-related protein 1). DRP1i27 binds to the GTPase site of Drp1, with hydrogen bonds to Gln34 and Asp218. DRP1i27 targets Drp1-mediated mitochondrial fission in cell line models and protects against simulated ischemia-reperfusion injury. | ||||||||||||||||||||
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