146897-68-9
Chemical Structure
Lactoferrin (17-41)
Synonym(s): Lactoferricin B; Lfcin B
- CAS 番号: 146897-68-9
- Formula:C141H224N46O29S3
- Molecular Weight:3123.77
SMILES: O=C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N1[C@](CCC1)([H])C(N[C@H](C(N[C@@](C(N[C@@](C(N[C@@H](CSSC[C@@H](C(N[C@H](C(N[C@H](C(N2)=O)CCCNC(N)=N)=O)CCCNC(N)=N)=O)NC([C@H](CCCCN)NC([C@@H](N)CC3=CC=CC=C3)=O)=O)C(N[C@@H](C(C)C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](C)C(N[C@H](C(O)=O)CC4=CC=CC=C4)=O)=O)=O)=O)=O)=O)([H])[C@H](O)C)=O)([H])[C@@H](C)CC)=O)CO)=O)=O)C)=O)=O)CC(C)C)=O)CCCCN)=O)CCCCN)=O)CCSC)=O)CCCNC(N)=N)=O)CC5=CNC6=CC=CC=C56)=O)CCC(N)=O)[C@@H]2CC7=CNC8=CC=CC=C78
Biological Activity: Lactoferrin 17-41 (Lactoferricin B), a peptide corresponding to residues 17-41 of bovine lactoferrin, has antimicrobial activity against a wide range of microorganisms, including Gram-positive and Gramnegative bacteria, viruses, protozoa, and fungi. Lactoferrin 17-41 has antitumor activities[1][2].
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Lactoferrin (17-41) | 98.98% | Lactoferrin 17-41 (Lactoferricin B), a peptide corresponding to residues 17-41 of bovine lactoferrin, has antimicrobial activity against a wide range of microorganisms, including Gram-positive and Gramnegative bacteria, viruses, protozoa, and fungi. Lactoferrin 17-41 has antitumor activities. | ||||||||||||||||||||
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- [1]. Samuelsen Ø, et al. Anti-complement effects of lactoferrin-derived peptides. FEMS Immunol Med Microbiol. 2004 Jun 1;41(2):141-8. [Content Brief]
- [2]. Jiang R, et al. Bovine lactoferrin and lactoferricin exert antitumor activities on human colorectal cancer cells(HT-29) by activating various signaling pathways. Biochem Cell Biol. 2017 Feb;95(1):99-109. [Content Brief]
Keywords
