1469337-95-8
1469337-95-8
Chemical Structure
K-Ras(G12C) inhibitor 12
- CAS 番号: 1469337-95-8
- Formula:C15H17ClIN3O3
- Molecular Weight:449.67
IUPAC Name: 1-(4-((4-chloro-2-hydroxy-5-iodophenyl)glycyl)piperazin-1-yl)prop-2-en-1-one
InChIKey: JFIFBWVNHLXJFY-UHFFFAOYSA-N
SMILES: C=CC(N1CCN(C(CNC2=CC(I)=C(Cl)C=C2O)=O)CC1)=O
Biological Activity: K-Ras(G12C) inhibitor 12 is an irreversible inhibitor of K-Ras(G12C). K-Ras(G12C) inhibitor 12 can alter the nucleotide-binding preference of K-Ras and block its interaction with effector proteins. K-Ras(G12C) inhibitor 12 can reduce cell viability and induce apoptosis in lung cancer cell lines with G12C mutations. K-Ras(G12C) inhibitor 12 has anti-tumor activity[1].
| 製品番号 | 製品名 | 純度 | 製品説明 | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
K-Ras(G12C) inhibitor 12 | 99.57% | K-Ras(G12C) inhibitor 12 is an irreversible inhibitor of K-Ras(G12C). K-Ras(G12C) inhibitor 12 can alter the nucleotide-binding preference of K-Ras and block its interaction with effector proteins. K-Ras(G12C) inhibitor 12 can reduce cell viability and induce apoptosis in lung cancer cell lines with G12C mutations. K-Ras(G12C) inhibitor 12 has anti-tumor activity. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
