147751-31-3
147751-31-3
Chemical Structure
HDL376
Synonym(s): SDZ-HDL 376
- CAS No.: 147751-31-3
- Formula:C12H17ClN2S
- Molecular Weight:256.79
IUPAC Name: 1-(5-chloro-2-methylphenyl)-3-isobutylthiourea
InChIKey: CVLONJGXRCEARL-UHFFFAOYSA-N
SMILES: S=C(NC1=CC(Cl)=CC=C1C)NCC(C)C
Biological Activity: HDL376 is a scavenger receptor class B type I (SR-BI) inhibitor. HDL376 directly inhibits SR-BI-mediated lipid transport in cells and in liposomes reconstituted with purified SR-BI (IC50 = 0.22 μM). HDL376 can be used for the research of atherosclerotic coronary artery disease[1].
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HDL376 | 98.62% | HDL376 is a scavenger receptor class B type I (SR-BI) inhibitor. HDL376 directly inhibits SR-BI-mediated lipid transport in cells and in liposomes reconstituted with purified SR-BI (IC50 = 0.22 μM). HDL376 can be used for the research of atherosclerotic coronary artery disease. | ||||||||||||||||||||
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References
Keywords
