1508250-71-2
1508250-71-2
Chemical Structure
Nazartinib
Synonym(s): EGF816
- CAS No.: 1508250-71-2
- Formula:C26H31ClN6O2
- Molecular Weight:495.02
IUPAC Name: (R,E)-N-(7-chloro-1-(1-(4-(dimethylamino)but-2-enoyl)azepan-3-yl)-1H-benzo[d]imidazol-2-yl)-2-methylisonicotinamide
InChIKey: IOMMMLWIABWRKL-WUTDNEBXSA-N
SMILES: O=C(C1=CC(C)=NC=C1)NC2=NC3=CC=CC(Cl)=C3N2[C@H]4CN(C(/C=C/CN(C)C)=O)CCCC4
Biological Activity: Nazartinib (EGF816) is a covalent mutant-selective EGFR inhibitor, with Ki and Kinact of 31 nM and 0.222 min−1 on EGFR(L858R/790M) mutant, respectively.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Nazartinib | 99.53% | Nazartinib (EGF816) is a covalent mutant-selective EGFR inhibitor, with Ki and Kinact of 31 nM and 0.222 min−1 on EGFR(L858R/790M) mutant, respectively. | ||||||||||||||||||||
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