154992-24-2
154992-24-2
Chemical Structure
RU 58841
Synonym(s): PSK-3841; HMR-3841
- CAS No.: 154992-24-2
- Formula:C17H18F3N3O3
- Molecular Weight:369.34
IUPAC Name: 4-(3-(4-hydroxybutyl)-4,4-dimethyl-2,5-dioxoimidazolidin-1-yl)-2-(trifluoromethyl)benzonitrile
InChIKey: ARBYGDBJECGMGA-UHFFFAOYSA-N
SMILES: FC(F)(C1=C(C=CC(N2C(C(C)(N(C2=O)CCCCO)C)=O)=C1)C#N)F
Biological Activity: RU 58841 (PSK-3841) is a specific androgen receptor antagonist or anti-androgen. RU 58841 has a dramatic effect on hair regrowth[1][2][3].
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RU 58841 | 99.72% | RU 58841 (PSK-3841) is a specific androgen receptor antagonist or anti-androgen. RU 58841 has a dramatic effect on hair regrowth. | ||||||||||||||||||||
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RU 58841 (Standard) | ≥98% | RU 58841 (Standard) is the analytical standard of RU 58841 (HY-10561). This product is intended for research and analytical applications. RU 58841 (PSK-3841) is a specific androgen receptor antagonist or anti-androgen. RU 58841 has a dramatic effect on hair regrowth. | ||||||||||||||||||||
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References
- [1]. A controlled study of the effects of RU58841, a non-steroidal antiandrogen, on human hair production by balding scalp grafts maintained on testosterone-conditioned nude mice By De Brouwer, B.; Tetelin, C.; Leroy, T.; Bonfils, A.; Van Neste, D. .From British Journal of Dermatology (1997), 137(5), 699-702. [Content Brief]
- [2]. Münster U, Nakamura C, Haberland A, Jores K, Mehnert W, Rummel S, Schaller M, Korting HC, Zouboulis ChC, Blume-Peytavi U, Sch?fer-Korting M.RU 58841-myristate--prodrug development for topical treatment of acne and androgenetic alopecia.Pharmazie. 2005 Jan;60(1):8-12. [Content Brief]
- [3]. Battmann T, Bonfils A, Branche C, Humbert J, Goubet F, Teutsch G, Philibert D.RU 58841, a new specific topical antiandrogen: a candidate of choice for the treatment of acne, androgenetic alopecia and hirsutism.J Steroid Biochem Mol Biol. 1994 Jan;48(1):55-60. [Content Brief]
