1630086-20-2
1630086-20-2
Chemical Structure
Kira8
Synonym(s): AMG-18
- CAS No.: 1630086-20-2
- Formula:C31H29ClN6O3S
- Molecular Weight:601.12
IUPAC Name: (S)-2-chloro-N-(6-methyl-5-((3-(2-(piperidin-3-ylamino)pyrimidin-4-yl)pyridin-2-yl)oxy)naphthalen-1-yl)benzenesulfonamide
InChIKey: XMWUCMFVDXDRDE-NRFANRHFSA-N
SMILES: O=S(C1=CC=CC=C1Cl)(NC2=C3C=CC(C)=C(OC4=NC=CC=C4C5=NC(N[C@@H]6CNCCC6)=NC=C5)C3=CC=C2)=O
Biological Activity: Kira8 (AMG-18) is a mono-selective IRE1α inhibitor that allosterically attenuates IRE1α RNase activity with an IC50 of 5.9 nM[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Kira8 | 98.90% | Kira8 (AMG-18) is a mono-selective IRE1α inhibitor that allosterically attenuates IRE1α RNase activity with an IC50 of 5.9 nM. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
Keywords
