1638667-79-4
1638667-79-4
Chemical Structure
LY3154207
- CAS No.: 1638667-79-4
- Formula:C24H29Cl2NO3
- Molecular Weight:450.40
IUPAC Name: 2-(2,6-dichlorophenyl)-1-((1S,3R)-5-(3-hydroxy-3-methylbutyl)-3-(hydroxymethyl)-1-methyl-3,4-dihydroisoquinolin-2(1H)-yl)ethan-1-one
InChIKey: XHCSBQBBGNQINS-DOTOQJQBSA-N
SMILES: O=C(N1[C@@H](C)C2=C(C(CCC(C)(O)C)=CC=C2)C[C@@H]1CO)CC3=C(Cl)C=CC=C3Cl
Biological Activity: LY3154207 is a potent, subtype selective, and orally available human dopamine D1 receptor positive allosteric modulator (PAM) with minimal allosteric agonist activity (EC50=3 nM)[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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LY3154207 | 98.06% | LY3154207 is a potent, subtype selective, and orally available human dopamine D1 receptor positive allosteric modulator (PAM) with minimal allosteric agonist activity (EC50=3 nM). | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.82
HY-115553DETQ -
Similarity Score 0.66
HY-144291LY3154885 -
Similarity Score 0.50
HY-139059ERD03 -
Similarity Score 0.47
HY-120045DuP 747 -
Similarity Score 0.46
HY-120045ADuP 747 hydrochloride -
Similarity Score 0.46
HY-128865BPR1M97 -
Similarity Score 0.45
HY-101205ICI-199441 hydrochloride -
Similarity Score 0.45
HY-W023852RN-(4-Chlorophenyl)-2-(2,6-dichlorophenyl)acetamide (Standard) -
Similarity Score 0.45
HY-18617rel-SB-612111 hydrochloride -
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