1677667-24-1
1677667-24-1
Chemical Structure
GNE-0946
- CAS No.: 1677667-24-1
- Formula:C22H12ClF3N2O4
- Molecular Weight:460.79
IUPAC Name: 4-(3-(2-chloro-6-(trifluoromethyl)benzoyl)imidazo[1,5-a]pyridin-1-yl)-2-hydroxybenzoic acid
InChIKey: UAAUZNSONHHQQI-UHFFFAOYSA-N
SMILES: OC1=CC(C2=C3N(C(C(C4=C(C(F)(F)F)C=CC=C4Cl)=O)=N2)C=CC=C3)=CC=C1C(O)=O
Biological Activity: GNE-0946 is a potent and selective RORγ( RORc) agonist with an EC50 value of 4 nM for HEK-293 cell.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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GNE-0946 | 98.11% | GNE-0946 is a potent and selective RORγ( RORc) agonist with an EC50 value of 4 nM for HEK-293 cell. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.64
HY-19775GNE-6468 -
Similarity Score 0.49
HY-149953FABP4-IN-2 -
Similarity Score 0.47
HY-W1124214,4'-(Naphthalene-1,4-diyl)bis(2-hydroxybenzoic acid) -
Similarity Score 0.47
HY-148899Mcl-1 inhibitor 10 -
Similarity Score 0.47
![3,3''-Bis(trifluoromethyl)-[1,1':4',1''-terphenyl]-4,4''-dicarboxylic acid Chemical Structure](//file.medchemexpress.com/product_pic/hy-w456351.gif)
HY-W4563513,3''-Bis(trifluoromethyl)-[1,1':4',1''-terphenyl]-4,4''-dicarboxylic acid -
Similarity Score 0.46
HY-161523XOR/URAT1-IN-1 -
Similarity Score 0.46
HY-117457BPIC -
Similarity Score 0.46
HY-18509IRE1α kinase-IN-2 -
Similarity Score 0.46
HY-115549AMPK activator 18 -
Explore the MedChemAI to find more analogs
![3,3''-Bis(trifluoromethyl)-[1,1':4',1''-terphenyl]-4,4''-dicarboxylic acid Chemical Structure](http://file.medchemexpress.com/product_pic/hy-w456351.gif)
