175140-00-8
175140-00-8
Chemical Structure
CP 376395
- CAS No.: 175140-00-8
- Formula:C21H30N2O
- Molecular Weight:326.48
IUPAC Name: 2-(mesityloxy)-3,6-dimethyl-N-(pentan-3-yl)pyridin-4-amine
InChIKey: VIZBSVDBNLAVAW-UHFFFAOYSA-N
SMILES: CCC(CC)NC1=C(C)C(OC2=C(C)C=C(C)C=C2C)=NC(C)=C1
Biological Activity: CP 376395 is a potent, selective, and brain-penetrable Corticotropin releasing factor 1 (CRF1) receptor antagonist[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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CP 376395 | 99.59% | CP 376395 is a potent, selective, and brain-penetrable Corticotropin releasing factor 1 (CRF1) receptor antagonist. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.98
HY-103379CP 376395 hydrochloride -
Similarity Score 0.78
HY-14129CP 316311 -
Similarity Score 0.53
HY-120737L-702007 -
Similarity Score 0.52
HY-118912BMH-9 -
Similarity Score 0.52
HY-118723BMH-22 -
Similarity Score 0.52
HY-N19903Verticilatin -
Similarity Score 0.52
HY-N19799Diorcinol D -
Similarity Score 0.51
HY-N7374Cyperin -
Similarity Score 0.50
HY-116738Trimecaine -
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References
- [1]. Chen YL, et al. 2-aryloxy-4-alkylaminopyridines: discovery of novel corticotropin-releasing factor 1 antagonists. J Med Chem. 2008 Mar 13;51(5):1385-92. [Content Brief]
- [2]. Giardino WJ, et al. CRF1 receptor signaling regulates food and fluid intake in the drinking-in-the-dark model of binge alcohol consumption. Alcohol Clin Exp Res. 2013 Jul;37(7):1161-70. [Content Brief]
