1769-24-0
1769-24-0
Chemical Structure
2-Methylquinazolin-4-ol
- CAS. Nr.: 1769-24-0
- Formula:C9H8N2O
- Molecular Weight:160.17
IUPAC Name: 2-methylquinazolin-4(3H)-one
InChIKey: FIEYHAAMDAPVCH-UHFFFAOYSA-N
SMILES: O=C1NC(C)=NC2=C1C=CC=C2
Biological Activity: 2-Methylquinazolin-4-ol is a potent competitive poly(ADP-ribose) synthetase inhibitor, with a Ki of 1.1 μM. 2-Methylquinazolin-4-ol mammalian aspartate transcarbamylase (ATCase) inhibitor, with 0.20 mM[1][2].
| Art. -Nr. | Produktname | Reinheit | Beschreibung | Pricing | |||||||||||||||||||
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2-Methylquinazolin-4-ol | 99.95% | 2-Methylquinazolin-4-ol is a potent competitive poly(ADP-ribose) synthetase inhibitor, with a Ki of 1.1 μM. 2-Methylquinazolin-4-ol mammalian aspartate transcarbamylase (ATCase) inhibitor, with 0.20 mM. | ||||||||||||||||||||
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2-Methylquinazolin-4-ol (Standard) | ≥98% | 2-Methylquinazolin-4-ol (Standard) is the analytical standard of 2-Methylquinazolin-4-ol. This product is intended for research and analytical applications. 2-Methylquinazolin-4-ol is a potent competitive poly(ADP-ribose) synthetase inhibitor, with a Ki of 1.1 μM. 2-Methylquinazolin-4-ol mammalian aspartate transcarbamylase (ATCase) inhibitor, with 0.20 mM. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.90
HY-1184363-Methyl-2-quinoxalinone -
Similarity Score 0.86
HY-15044NU1025 -
Similarity Score 0.86
HY-W034419STIMA-1 -
Similarity Score 0.84
HY-N9550Chrysogine -
Similarity Score 0.84
HY-W0188004(3H)-Quinazolinone -
Similarity Score 0.82
HY-W1061092-Hydroxy-4-methylquinoline -
Similarity Score 0.81
HY-N7089RBenzoyleneurea (Standard) -
Similarity Score 0.81
HY-W349178Medorinone -
Similarity Score 0.79
HY-W017519R2-Quinoxalinol (Standard) -
Explore the MedChemAI to find more analogs
References
- [1]. S Yoshida, et al. Production of 2-methyl-4[3H]-quinazolinone, an inhibitor of poly(ADP-ribose) synthetase, by bacterium. J Antibiot (Tokyo). 1991 Jan;44(1):111-2. [Content Brief]
- [2]. Mahmoud Balbaa, et al. Inhibition of mammalian aspartate transcarbamylase by quinazolinone derivatives. J Enzyme Inhib Med Chem. 2008 Aug;23(4):483-92. [Content Brief]
