179985-52-5
179985-52-5
Chemical Structure
PKA-IN-1
- CAS No.: 179985-52-5
- Formula:C13H11N3O
- Molecular Weight:225.25
IUPAC Name: N-(4-cyano-3-methylisoquinolin-1-yl)acetamide
InChIKey: SRNACQXBALMDDC-UHFFFAOYSA-N
SMILES: CC(NC1=NC(C)=C(C#N)C2=C1C=CC=C2)=O
Biological Activity: PKA-IN-1 is a potent and selective cyclic AMP-dependent protein kinase (PKA) catalytic subunit (cAK) inhibitor with an IC50 of 0.03 μM. PKA-IN-1 inhibits cAK in a fashion that is competitive with respect to ATP as substrate[1].
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PKA-IN-1 | 99.82% | PKA-IN-1 is a potent and selective cyclic AMP-dependent protein kinase (PKA) catalytic subunit (cAK) inhibitor with an IC50 of 0.03 μM. PKA-IN-1 inhibits cAK in a fashion that is competitive with respect to ATP as substrate. | ||||||||||||||||||||
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References
Keywords
