1802518-63-3
Chemical Structure
(Rac)-Minzasolmin
Synonym(s): (Rac)-UCB0599; NPT200-11
- CAS No.: 1802518-63-3
- Formula:C23H31N5OS
- Molecular Weight:425.59
IUPAC Name: N-(1-(1H-indol-3-yl)hexan-2-yl)-2-(4-methylpiperazin-1-yl)thiazole-5-carboxamide
InChIKey: GDFWCSZNQVAQGR-UHFFFAOYSA-N
SMILES: O=C(C1=CN=C(N2CCN(CC2)C)S1)NC(CCCC)CC3=CNC4=CC=CC=C34
Biological Activity: (Rac)-Minzasolmin ((Rac)-UCB0599; NPT200-11) is a blood-brain barrier penetrated alpha-synuclein (ASYN) misfolding inhibitor. (Rac)-Minzasolmin acts on the early stage of ASYN aggregation process, by replacing the membrane-bound oligomers ASYN, allowing them to revert to the monomeric form, while preventing pathological aggregation. (Rac)-Minzasolmin effectively improves the ASYN deposition in the retina and the neuro-pathological indicators in two α-synuclein transgenic mouse models. (Rac)-Minzasolmin can be used for the studies of Parkinson's disease (PD) and dementia with Lewy bodies (DLB)[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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(Rac)-Minzasolmin | 99.87% | (Rac)-Minzasolmin ((Rac)-UCB0599; NPT200-11) is a blood-brain barrier penetrated alpha-synuclein (ASYN) misfolding inhibitor. (Rac)-Minzasolmin acts on the early stage of ASYN aggregation process, by replacing the membrane-bound oligomers ASYN, allowing them to revert to the monomeric form, while preventing pathological aggregation. (Rac)-Minzasolmin effectively improves the ASYN deposition in the retina and the neuro-pathological indicators in two α-synuclein transgenic mouse models. (Rac)-Minzasolmin can be used for the studies of Parkinson's disease (PD) and dementia with Lewy bodies (DLB). | ||||||||||||||||||||
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