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Art. -Nr.: HY-139825

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Indoluidin E

Indoluidin E selectively inhibits DHODH and suppresses cancer cell growth.

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CAS. Nr.: 2763081-76-9
Formel: C₂₈H₃₀N₄O₂
Molecular Weight:454.56

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

Indoluidin E Chemical Structure

CAS. Nr.: 2763081-76-9

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- Cellular Effect
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

Indoluidin E selectively inhibits DHODH and suppresses cancer cell growth.

Cellular Effect

Cell Line	Type	Value	Description	References
A549	IC₅₀	42 nM Compound: 50	Antiproliferative activity against human A549 cells Antiproliferative activity against human A549 cells	[PMID: 35151222]
HL-60	EC₅₀	7.3 nM Compound: 50	Induction of cell differentiation in human HL-60 cells Induction of cell differentiation in human HL-60 cells	[PMID: 35151222]

Chemical Information

CAS. Nr. 2763081-76-9
Molecular Weight 454.56
Formel C₂₈H₃₀N₄O₂
SMILES

O=C(N[C@H](CC1=CNC2=C1C=CC=C2)C(NC3=CC=C(C)C=C3)=O)C4=NC=C(CCCC)C=C4
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Kawatani M, et al. Identification of Dihydroorotate Dehydrogenase Inhibitors─Indoluidins─That Inhibit Cancer Cell Growth. ACS Chem Biol. 2021 Nov 19;16(11):2570-2580. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

Minimum order quantity

100 mg

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