1803003-65-7
1803003-65-7
Chemical Structure
RN-1665
- CAS No.: 1803003-65-7
- Formula:C20H24F5N3O3S2
- Molecular Weight:513.54
InChIKey: LXVDSGFXMXYFGL-UHFFFAOYSA-N
SMILES: O=C(C1=CC=C(S(F)(F)(F)(F)F)C=C1)NC2=CC=C(S(=O)(N3CCN(C(C)C)CC3)=O)C=C2
Biological Activity: RN-1665 is an orally active TRPV4 antagonist that exhibits excellent selectivity for related TRP receptors such as TRPV1, TRPV3 and TRPM8. RN-1665 is a TRPV4 probe for focus screens, with IC50s of 0.26 μM and 0.39 μM for hTRPV4 and rTRPV4 from human and rat, respectively[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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RN-1665 | 99.93% | RN-1665 is an orally active TRPV4 antagonist that exhibits excellent selectivity for related TRP receptors such as TRPV1, TRPV3 and TRPM8. RN-1665 is a TRPV4 probe for focus screens, with IC50s of 0.26 μM and 0.39 μM for hTRPV4 and rTRPV4 from human and rat, respectively. | ||||||||||||||||||||
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References
Keywords
