1803003-65-7
1803003-65-7
Chemical Structure
RN-1665
- CAS No.: 1803003-65-7
- Formula:C20H24F5N3O3S2
- Molecular Weight:513.54
InChIKey: LXVDSGFXMXYFGL-UHFFFAOYSA-N
SMILES: O=C(C1=CC=C(S(F)(F)(F)(F)F)C=C1)NC2=CC=C(S(=O)(N3CCN(C(C)C)CC3)=O)C=C2
Biological Activity: RN-1665 is an orally active TRPV4 antagonist that exhibits excellent selectivity for related TRP receptors such as TRPV1, TRPV3 and TRPM8. RN-1665 is a TRPV4 probe for focus screens, with IC50s of 0.26 μM and 0.39 μM for hTRPV4 and rTRPV4 from human and rat, respectively[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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RN-1665 | 99.93% | RN-1665 is an orally active TRPV4 antagonist that exhibits excellent selectivity for related TRP receptors such as TRPV1, TRPV3 and TRPM8. RN-1665 is a TRPV4 probe for focus screens, with IC50s of 0.26 μM and 0.39 μM for hTRPV4 and rTRPV4 from human and rat, respectively. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.69
HY-162765TRPV4-IN-5 -
Similarity Score 0.67
HY-110270RN-9893 -
Similarity Score 0.67
HY-110270ARN-9893 hydrochloride -
Similarity Score 0.66
HY-Q43097Hsp110-STAT3 PPI-IN-1 -
Similarity Score 0.59
HY-171007IRF1-IN-2 -
Similarity Score 0.56
HY-163445NAMPT activator-6 -
Similarity Score 0.55
HY-14240PG 116800 -
Similarity Score 0.55
HY-N12659Thaumatin B -
Similarity Score 0.54
HY-146342FAAH/MAGL-IN-3 -
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