1855871-76-9
1855871-76-9
Chemical Structure
V-9302
- CAS No.: 1855871-76-9
- Formula:C34H38N2O4
- Molecular Weight:538.68
IUPAC Name: (S)-2-amino-4-(bis(2-((3-methylbenzyl)oxy)benzyl)amino)butanoic acid
InChIKey: YGKNVAAMULVFNN-HKBQPEDESA-N
SMILES: O=C(O)[C@@H](N)CCN(CC1=CC=CC=C1OCC2=CC=CC(C)=C2)CC3=CC=CC=C3OCC4=CC=CC(C)=C4
Biological Activity: V-9302 is a competitive antagonist of transmembrane glutamine flux. V-9302 selectively and potently targets the amino acid transporter ASCT2 (SLC1A5) not ASCT1. V-9302 inhibits ASCT2-mediated glutamine uptake (IC50=9.6 μM) in HEK-293 cells[1].
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V-9302 | 99.46% | V-9302 is a competitive antagonist of transmembrane glutamine flux. V-9302 selectively and potently targets the amino acid transporter ASCT2 (SLC1A5) not ASCT1. V-9302 inhibits ASCT2-mediated glutamine uptake (IC50=9.6 μM) in HEK-293 cells. | ||||||||||||||||||||
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References
Keywords
