189954-96-9
189954-96-9
Chemical Structure
Firocoxib
Synonym(s): ML 1785713
- No. CAS: 189954-96-9
- Formula:C17H20O5S
- Molecular Weight:336.40
IUPAC Name: 3-(cyclopropylmethoxy)-5,5-dimethyl-4-(4-(methylsulfonyl)phenyl)furan-2(5H)-one
InChIKey: FULAPETWGIGNMT-UHFFFAOYSA-N
SMILES: O=C1OC(C)(C)C(C2=CC=C(S(=O)(C)=O)C=C2)=C1OCC3CC3
Biological Activity: Firocoxib (ML 1785713) is a potent, selective and orally active COX-2 inhibitor with an IC50 of 0.13 μM. Firocoxib shows 58-fold more selective for COX-2 than COX-1 (IC50 of 7.5 μM). Firocoxib has anti-inflammatory effects[1].
| Referencia número | Nombre del producto | Pureza | Descripciòn | Pricing | |||||||||||||||||||
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Firocoxib | 99.54% | Firocoxib (ML 1785713) is a potent, selective and orally active COX-2 inhibitor with an IC50 of 0.13 μM. Firocoxib shows 58-fold more selective for COX-2 than COX-1 (IC50 of 7.5 μM). Firocoxib has anti-inflammatory effects. | ||||||||||||||||||||
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Firocoxib (Standard) | ≥98% | Firocoxib (Standard) is the analytical standard of Firocoxib. This product is intended for research and analytical applications. Firocoxib (ML 1785713) is a potent, selective and orally active COX-2 inhibitor with an IC50 of 0.13 μM. Firocoxib shows 58-fold more selective for COX-2 than COX-1 (IC50 of 7.5 μM). Firocoxib has anti-inflammatory effects. | ||||||||||||||||||||
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Firocoxib-d4 | Firocoxib-d4 (ML 1785713-d4) is the deuterium labeled Firocoxib. Firocoxib (ML 1785713) is a potent, selective and orally active COX-2 inhibitor with an IC50 of 0.13 μM. Firocoxib shows 58-fold more selective for COX-2 than COX-1 (IC50 of 7.5 μM). Firocoxib has anti-inflammatory effects. | |||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.76
HY-105304COX-2-IN-36 -
Similarity Score 0.57
HY-17372RRofecoxib (Standard) -
Similarity Score 0.55
HY-105485FR-62765 -
Similarity Score 0.54
HY-17372SRofecoxib-d5 -
Similarity Score 0.54
HY-105290DRF-4848 -
Similarity Score 0.53
HY-U00129SC57666 -
Similarity Score 0.53
HY-118691BMS-347070 -
Similarity Score 0.52
HY-155164WF-3681 -
Similarity Score 0.50
HY-106981Orazipone -
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