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Cat. No.: HY-105304

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COX-2-IN-36

COX-2-IN-36 (compound 1) is a very potent and specific COX-2 inhibitor, with an IC₅₀ of 0.4 μM.

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CAS No.: 189954-93-6
Formule: C₁₇H₂₂O₅S
Masse moléculaire:338.42

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (273 KB)

COX-2-IN-36 Chemical Structure

CAS No.: 189954-93-6

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- IC₅₀ & Target
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
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Activité biologique

Description

COX-2-IN-36 (compound 1) is a very potent and specific COX-2 inhibitor, with an IC₅₀ of 0.4 μM^[1]^[2].

IC₅₀ & Target

IC50: 0.4 μM (COX-2)^[2].

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Chemical Information

CAS No. 189954-93-6
Masse moléculaire 338.42
Formule C₁₇H₂₂O₅S
SMILES

CC(C)OC1=C(C2=CC=C(C=C2)S(C)(=O)=O)[C@@](C)(OC1=O)CC
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (273 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Lushi Tan, et al. Practical enantioselective synthesis of a COX-2 specific inhibitor. Tetrahedron Volume 58, Issue 37, 9 September 2002, Pages 7403-7410.

[2]. Yves Leblanc, et al. Discovery of a potent and selective COX-2 inhibitor in the alkoxy lactone series with optimized metabolic profile. Bioorg Med Chem Lett. 2002 Nov 18;12(22):3317-20. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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Chemical Information
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COX-2-IN-36

Voir tous les produits spécifiques à Isoform COX

Activité biologique

Description

IC50 & Target

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

COX-2-IN-36 Related Classifications

HY-105304 Related Classifications

Bioz

Keywords

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