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Cat. No.: HY-105304

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COX-2-IN-36

COX-2-IN-36 (compound 1) is a very potent and specific COX-2 inhibitor, with an IC₅₀ of 0.4 μM.

For research use only. We do not sell to patients.

CAS No.: 189954-93-6
Formula: C₁₇H₂₂O₅S
Molecular Weight:338.42

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (273 KB)

COX-2-IN-36 Chemical Structure

CAS No.: 189954-93-6

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Sample (0.1mg)

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(In Japan)

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Bioz

Biological Activity

Description

COX-2-IN-36 (compound 1) is a very potent and specific COX-2 inhibitor, with an IC₅₀ of 0.4 μM^[1]^[2].

IC₅₀ & Target

IC50: 0.4 μM (COX-2)^[2].

All COX Isoforms :

Chemical Information

CAS No. 189954-93-6
Molecular Weight 338.42
Formula C₁₇H₂₂O₅S
SMILES

CC(C)OC1=C(C2=CC=C(C=C2)S(C)(=O)=O)[C@@](C)(OC1=O)CC
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (273 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Lushi Tan, et al. Practical enantioselective synthesis of a COX-2 specific inhibitor. Tetrahedron Volume 58, Issue 37, 9 September 2002, Pages 7403-7410.

[2]. Yves Leblanc, et al. Discovery of a potent and selective COX-2 inhibitor in the alkoxy lactone series with optimized metabolic profile. Bioorg Med Chem Lett. 2002 Nov 18;12(22):3317-20. [Content Brief]

Calculators

Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Dilution Calculator

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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