1918159-31-5
1918159-31-5
Chemical Structure
Epaldeudomide
- CAS No.: 1918159-31-5
- Formula:C25H25DFN3O5
- Molecular Weight:468.50
InChIKey: LSWTTWZVLFJNEN-VKXNLOJKSA-N
SMILES: FC(C=C(C=C1)CN2CCOCC2)=C1COC3=C4C(C(N([C@]5([2H])C(NC(CC5)=O)=O)C4)=O)=CC=C3
Biological Activity: Epaldeudomide (Compound A406) is the inhibitor for TNF-α (>50% inhibition rate at 100 nM). Epaldeudomide inhibits the proliferation of cancer cells MM.1S (IC50 < 300 nM), WSU-DLCL-2 (IC50 < 100 nM) and Rec-1 (IC50 < 100 nM). Epaldeudomide exhibits antineoplastic activity[1].
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Epaldeudomide | Epaldeudomide (Compound A406) is the inhibitor for TNF-α (>50% inhibition rate at 100 nM). Epaldeudomide inhibits the proliferation of cancer cells MM.1S (IC50 < 300 nM), WSU-DLCL-2 (IC50 < 100 nM) and Rec-1 (IC50 < 100 nM). Epaldeudomide exhibits antineoplastic activity. | |||||||||||||||||||||
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References
Keywords
