195875-68-4
195875-68-4
Chemical Structure
NS2359
Synonym(s): GSK372475
- CAS No.: 195875-68-4
- Formula:C16H21Cl2NO
- Molecular Weight:314.25
IUPAC Name: (1R,2R,3S,5S)-3-(3,4-dichlorophenyl)-2-(methoxymethyl)-8-methyl-8-azabicyclo[3.2.1]octane
InChIKey: PGYDXVBZYKQYCS-VPWBDBDCSA-N
SMILES: COC[C@@H]1[C@@H](C2=CC(Cl)=C(C=C2)Cl)C[C@@]3([H])N([C@]1([H])CC3)C
Biological Activity: NS2359 (GSK372475) is a serotonin-norepinephrine-dopamine triple reuptake inhibitor. NS2359 is used for research on depression[1].
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NS2359 | NS2359 (GSK372475) is a serotonin-norepinephrine-dopamine triple reuptake inhibitor. NS2359 is used for research on depression. | |||||||||||||||||||||
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References
- [1]. Learned S, et al. Efficacy, safety, and tolerability of a triple reuptake inhibitor GSK372475 in the treatment of patients with major depressive disorder: two randomized, placebo- and active-controlled clinical trials. Journal of psychopharmacology (Oxford, England). 2012 May;26(5):653-62. [Content Brief]
Keywords
