201740-77-4
Chemical Structure
2-Deoxy-D-glucose-13C6
Synonym(s): 2-DG-13C6; 2-Deoxy-D-arabino-hexose-13C6; D-Arabino-2-deoxyhexose-13C6
- CAS No.: 201740-77-4
- Formula:13C6H12O5
- Molecular Weight:170.11
IUPAC Name: (3R,4S,5R)-3,4,5,6-tetrahydroxyhexanal-1,2,3,4,5,6-13C6
InChIKey: VRYALKFFQXWPIH-FBXUKYFESA-N
SMILES: O=[13CH][13CH2][13C@@H](O)[13C@H](O)[13C@H](O)[13CH2]O
Biological Activity: 2-Deoxy-D-glucose-13C6 (2-DG-13C6) is 13C labeled 2-Deoxy-D-glucose. 2-Deoxy-D-glucose is a glucose analog that acts as a competitive inhibitor of glucose metabolism, inhibiting glycolysis via its actions on hexokinase[1][2].
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2-Deoxy-D-glucose-13C6 | 2-Deoxy-D-glucose-13C6 (2-DG-13C6) is 13C labeled 2-Deoxy-D-glucose. 2-Deoxy-D-glucose is a glucose analog that acts as a competitive inhibitor of glucose metabolism, inhibiting glycolysis via its actions on hexokinase. | |||||||||||||||||||||
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2-Deoxy-D-glucose-d | 98.0% | 2-Deoxy-D-glucose-d is the deuterium labeled 2-Deoxy-D-glucose. 2-Deoxy-D-glucose is a glucose analog that acts as a competitive inhibitor of glucose metabolism, inhibiting glycolysis via its actions on hexokinase. | ||||||||||||||||||||
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2-Deoxy-D-glucose-13C | 99.48% | 2-Deoxy-D-glucose-13C is the 13C labeled 2-Deoxy-D-glucose. 2-Deoxy-D-glucose is a glucose analog that acts as a competitive inhibitor of glucose metabolism, inhibiting glycolysis via its actions on hexokinase. | ||||||||||||||||||||
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2-Deoxy-D-glucose-13C-1 | 2-Deoxy-D-glucose-13C-1 is the 13C labeled 2-Deoxy-D-glucose. 2-Deoxy-D-glucose is a glucose analog that acts as a competitive inhibitor of glucose metabolism, inhibiting glycolysis via its actions on hexokinase. | |||||||||||||||||||||
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2-Deoxy-D-glucose | 99.93% | 2-Deoxy-D-glucose is a glucose analog that acts as a competitive inhibitor of glucose metabolism, inhibiting glycolysis via its actions on hexokinase. | ||||||||||||||||||||
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- [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
- [2]. Miwa H, et al. Leukemia cells demonstrate a different metabolic perturbation provoked by 2-deoxyglucose. Oncol Rep. 2013 May;29(5):2053-7. [Content Brief]