2031152-08-4
2031152-08-4
Chemical Structure
XMU-MP-3
- CAS No.: 2031152-08-4
- Formula:C27H27F3N8O
- Molecular Weight:536.55
IUPAC Name: N-(3-(7-((1,3-dimethyl-1H-pyrazol-5-yl)amino)-1-methyl-1,4-dihydropyrimido[4,5-d]pyrimidin-3(2H)-yl)-4-methylphenyl)-3-(trifluoromethyl)benzamide
InChIKey: MCEWMWAJAOMTBE-UHFFFAOYSA-N
SMILES: O=C(NC1=CC=C(C)C(N2CC3=CN=C(NC4=CC(C)=NN4C)N=C3N(C)C2)=C1)C5=CC=CC(C(F)(F)F)=C5
Biological Activity: XMU-MP-3 is a potent non-covalent BTK inhibitor with IC50s of 10.7 nM and 17.0 nM for BTK WT and BTK C481S mutation in the presence of 10 μM ATP, respectively. XMU-MP-3 also induces apoptosis[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
XMU-MP-3 | 95.78% | XMU-MP-3 is a potent non-covalent BTK inhibitor with IC50s of 10.7 nM and 17.0 nM for BTK WT and BTK C481S mutation in the presence of 10 μM ATP, respectively. XMU-MP-3 also induces apoptosis. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Structural Analogs
-
Similarity Score 0.85
HY-10579RPluripotin (Standard) -
Similarity Score 0.75
HY-164400SIJ1777 -
Similarity Score 0.72
HY-122664XMU-MP-2 -
Similarity Score 0.71
HY-10943GNF-7 -
Similarity Score 0.70
HY-184006BMX ligand-1 -
Similarity Score 0.65
HY-176367Multi kinase ligand 4 -
Similarity Score 0.65
HY-160478GNF-6 -
Similarity Score 0.58
HY-101268CHMFL-ABL-053 -
Similarity Score 0.57
HY-163278Lck-IN-2 -
Explore the MedChemAI to find more analogs
