20362-54-3
20362-54-3
Chemical Structure
FBPase-IN-1
- CAS No.: 20362-54-3
- Formula:C6H4N2S4
- Molecular Weight:232.37
IUPAC Name: 1,2-di(thiazol-2-yl)disulfane
InChIKey: MZIWZDMEFARRSI-UHFFFAOYSA-N
SMILES: C1(SSC2=NC=CS2)=NC=CS1
Biological Activity: FBPase-IN-1 is a potent FBPase (Fructose-1,6-bisphosphatase) inhibitor for Type 2 diabetes (T2D) study with an IC50 of 0.22 μM. FBPase-IN-1 can reduce blood glucose levels and ameliorate glucose tolerance. FBPase-IN-1 modifies the C128 site, regulates the N125-S124-S123 allosteric pathway of FBPase and affects the catalytic activity of FBPase[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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FBPase-IN-1 | 98.07% | FBPase-IN-1 is a potent FBPase (Fructose-1,6-bisphosphatase) inhibitor for Type 2 diabetes (T2D) study with an IC50 of 0.22 μM. FBPase-IN-1 can reduce blood glucose levels and ameliorate glucose tolerance. FBPase-IN-1 modifies the C128 site, regulates the N125-S124-S123 allosteric pathway of FBPase and affects the catalytic activity of FBPase. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.70
HY-W1082761,2-Di(pyrimidin-2-yl)disulfane -
Similarity Score 0.68
HY-Y16662,2′-Dipyridyl disulfide -
Similarity Score 0.67
HY-346071,4-Dithiapentalene -
Similarity Score 0.67
HY-W0405841H,1'H-2,2'-Biimidazole -
Similarity Score 0.66
HY-151280Antifungal agent 37 -
Similarity Score 0.65
HY-151284Antifungal agent 38 -
Similarity Score 0.65
HY-W0124231,2-Di(pyridin-4-yl)disulfane -
Similarity Score 0.61
HY-12396Aminothiazole -
Similarity Score 0.61
HY-413402-Aminopyrimidine -
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