2055155-75-2
Chemical Structure
Jinflexin A
- CAS No.: 2055155-75-2
- Formula:C19H22O3
- Molecular Weight:298.38
IUPAC Name: 4-(1-methoxyethyl)-1,8-dimethyl-9,10-dihydrophenanthrene-2,7-diol
InChIKey: XPMKDCLPDROINI-UHFFFAOYSA-N
SMILES: OC(C(C)=C1CC2)=CC(C(OC)C)=C1C3=C2C(C)=C(O)C=C3
Biological Activity: Jinflexin A is a phenanthrene compound that can be extracted and isolated from the roots of the plant Juncus inflexus, and it is also a potential antibacterial agent. Jinflexin A significantly inhibits the proliferation of various human tumor cell lines, with a IC50 range of 12.9 μM to 24.7 μM. Jinflexin A can be used in research related to Methicillin (HY-121544)-resistant Staphylococcus aureus infections, breast cancer, cervical cancer, and ovarian cancer[1][2].
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Jinflexin A | Jinflexin A is a phenanthrene compound that can be extracted and isolated from the roots of the plant Juncus inflexus, and it is also a potential antibacterial agent. Jinflexin A significantly inhibits the proliferation of various human tumor cell lines, with a IC50 range of 12.9 μM to 24.7 μM. Jinflexin A can be used in research related to Methicillin (HY-121544)-resistant Staphylococcus aureus infections, breast cancer, cervical cancer, and ovarian cancer. | |||||||||||||||||||||
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References
- [1]. Kúsz N, et al. Juncaceae Species as Promising Sources of Phenanthrenes: Antiproliferative Compounds from Juncus maritimus Lam. Molecules. 2021 Feb 13;26(4):999.
- [2]. Tóth B, et al. Phenanthrenes from Juncus inflexus with Antimicrobial Activity against Methicillin-Resistant Staphylococcus aureus. Journal of natural products. 2016 Nov 23;79(11):2814-2823. [Content Brief]