2115702-83-3
2115702-83-3
Chemical Structure
TLR7/8 agonist 6
- CAS No.: 2115702-83-3
- Formula:C24H27N5O2
- Molecular Weight:417.50
IUPAC Name: methyl 4-amino-1-(4-(aminomethyl)benzyl)-2-isobutyl-1H-imidazo[4,5-c]quinoline-7-carboxylate
InChIKey: MZRQRPABQLFPGF-UHFFFAOYSA-N
SMILES: CCCCC1=NC2=C(N=C3C=C(C=CC3=C2N1CC4=CC=C(CN)C=C4)C(OC)=O)N
Biological Activity: TLR7/8 agonist 6 is a TLR7/8 agonist with EC50s of 0.18 μM and 5.34 μM in TLR7 or TLR8 HEK-SEAP reporter cells, respectively. TLR7/8 agonist 6 potently stimulates production of TNFα, IFNγ, and IL-1β. TLR7/8 agonist 6 can be used for research on cancer and infectious diseases[1].
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TLR7/8 agonist 6 | 98.93% | TLR7/8 agonist 6 is a TLR7/8 agonist with EC50s of 0.18 μM and 5.34 μM in TLR7 or TLR8 HEK-SEAP reporter cells, respectively. TLR7/8 agonist 6 potently stimulates production of TNFα, IFNγ, and IL-1β. TLR7/8 agonist 6 can be used for research on cancer and infectious diseases. | ||||||||||||||||||||
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References
Keywords
