212966-15-9
Chemical Structure
AC-178335
- CAS No.: 212966-15-9
- Formula:C49H63N13O7
- Molecular Weight:946.11
IUPAC Name: (2R,3R)-2-((R)-2-((R)-2-acetamido-3-(1H-imidazol-5-yl)propanamido)-3-phenylpropanamido)-N-((R)-1-(((R)-1-(((R)-1-amino-1-oxo-3-phenylpropan-2-yl)amino)-3-(1H-indol-3-yl)-1-oxopropan-2-yl)amino)-5-guanidino-1-oxopentan-2-yl)-3-methylpentanamide
InChIKey: ADIUJENJSJKNSC-FKJNZLKYSA-N
SMILES: CC(N[C@H](CC1=CN=CN1)C(N[C@H](CC2=CC=CC=C2)C(N[C@H]([C@H](C)CC)C(N[C@H](CCCNC(N)=N)C(N[C@@H](C(N[C@@H](C(N)=O)CC3=CC=CC=C3)=O)CC4=CNC5=CC=CC=C45)=O)=O)=O)=O)=O
Biological Activity: AC-178335 is a SRIF antagonist, with a Ki of 172 nM. AC-178335 blocks SRIF inhibition of adenylate cyclase in vitro (IC50=5.1 μM). AC-178335 induces GH release in anesthetized rats[1].
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AC-178335 | AC-178335 is a SRIF antagonist, with a Ki of 172 nM. AC-178335 blocks SRIF inhibition of adenylate cyclase in vitro (IC50=5.1 μM). AC-178335 induces GH release in anesthetized rats. | |||||||||||||||||||||
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