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Art. -Nr.: HY-125673

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AC-178335

AC-178335 is a SRIF antagonist, with a K_i of 172 nM. AC-178335 blocks SRIF inhibition of adenylate cyclase in vitro (IC₅₀=5.1 μM). AC-178335 induces GH release in anesthetized rats.

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CAS. Nr.: 212966-15-9
Formel: C₄₉H₆₃N₁₃O₇
Molecular Weight:946.11

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

AC-178335 Chemical Structure

CAS. Nr.: 212966-15-9

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität

Beschreibung

AC-178335 is a SRIF antagonist, with a K_i of 172 nM. AC-178335 blocks SRIF inhibition of adenylate cyclase in vitro (IC₅₀=5.1 μM). AC-178335 induces GH release in anesthetized rats^[1].

Alle Somatostatin Receptor Isoform-spezifische Produkte anzeigen :

Chemical Information

CAS. Nr. 212966-15-9
Molecular Weight 946.11
Formel C₄₉H₆₃N₁₃O₇
Sequence

Ac-{d-(His-Phe-Ile-Arg-Trp-Phe)}-NH2
Sequence Shortening

Ac-{d-(HFIRWF)}-NH2
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (258 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Baumbach WR, et, al. A linear hexapeptide somatostatin antagonist blocks somatostatin activity in vitro and influences growth hormone release in rats. Mol Pharmacol. 1998 Nov;54(5):864-73. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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