2136325-05-6
2136325-05-6
Chemical Structure
PARP7-IN-16 free base
- CAS No.: 2136325-05-6
- Formula:C25H27FN4O4
- Molecular Weight:466.50
InChIKey: WKXCQZQWHUTWSY-UHFFFAOYSA-N
SMILES: O=C(NC1=O)C2=CC=CC=C2N1CC3=CC=C(C(C(N4CCN(C(C4)=O)C(CC)CC)=O)=C3)F
Biological Activity: PARP7-IN-16 free base is the free base form of PARP7-IN-16 (HY-156419). PARP7-IN-16 free base is a selective and orally active inhibitor of PARP-1/2/7, with IC50s of 0.94, 0.87 and 0.21 nM, respectively. PARP7-IN-16 can be used for the research of breast cancer and prostate cancer[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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PARP7-IN-16 free base | 99.40% | PARP7-IN-16 free base is the free base form of PARP7-IN-16 (HY-156419). PARP7-IN-16 free base is a selective and orally active inhibitor of PARP-1/2/7, with IC50s of 0.94, 0.87 and 0.21 nM, respectively. PARP7-IN-16 can be used for the research of breast cancer and prostate cancer. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.89
HY-156419PARP7-IN-16 -
Similarity Score 0.80
HY-145328PARP-1/2-IN-1 -
Similarity Score 0.63
HY-137450Senaparib -
Similarity Score 0.63
HY-137450ASenaparib hydrochloride -
Similarity Score 0.55
HY-102035PARP-2-IN-1 -
Similarity Score 0.51
HY-10162Olaparib -
Similarity Score 0.51
HY-75706N-Descyclopropanecarbaldehyde Olaparib -
Similarity Score 0.50
HY-13536AZD-2461 -
Similarity Score 0.50
HY-136489AKU-0058948 hydrochloride -
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