2140317-08-2
Chemical Structure
Cromolyn-d5
Synonym(s): Cromoglycate-d5; Cromoglicic acid-d5; FPL-670-d5 free acid
- CAS No.: 2140317-08-2
- Formula:C23H11D5O11
- Molecular Weight:473.40
IUPAC Name: 5,5'-((2-hydroxypropane-1,3-diyl-1,1,2,3,3-d5)bis(oxy))bis(4-oxo-4H-chromene-2-carboxylic acid)
InChIKey: IMZMKUWMOSJXDT-VFNCYXODSA-N
SMILES: OC(C([2H])([2H])OC1=C2C(C=C(C(O)=O)OC2=CC=C1)=O)([2H])C([2H])([2H])OC3=C4C(C=C(C(O)=O)OC4=CC=C3)=O
Biological Activity: Cromolyn-d5 (Cromoglycate-d5) is the deuterium labeled Cromolyn (HY-B1619). Cromolyn (Cromoglycate) is an orally active GSK-3β inhibitor with an IC50 of 2.0 μM. Cromolyn is also a mast cell stabilizer that can inhibit the release of mediators from mast cells, regulate reflex bronchoconstriction, and reduce non-specific bronchial hyperreactivity, and Cromolyn can be used in the research of bronchial asthma. In addition, Cromolyn has multiple activities such as anti-inflammatory, anti-allergic, anti-histamine, anti-cancer, and neuroprotective effects[1].
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Cromolyn-d5 | Cromolyn-d5 (Cromoglycate-d5) is the deuterium labeled Cromolyn (HY-B1619). Cromolyn (Cromoglycate) is an orally active GSK-3β inhibitor with an IC50 of 2.0 μM. Cromolyn is also a mast cell stabilizer that can inhibit the release of mediators from mast cells, regulate reflex bronchoconstriction, and reduce non-specific bronchial hyperreactivity, and Cromolyn can be used in the research of bronchial asthma. In addition, Cromolyn has multiple activities such as anti-inflammatory, anti-allergic, anti-histamine, anti-cancer, and neuroprotective effects. | |||||||||||||||||||||
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Cromolyn (Standard) | 99.98% | Cromolyn (Standard) is the analytical standard of Cromolyn. This product is intended for research and analytical applications. Cromolyn (Cromoglycate) is an orally active GSK-3β inhibitor with an IC50 of 2.0 μM. Cromolyn is also a mast cell stabilizer that can inhibit the release of mediators from mast cells, regulate reflex bronchoconstriction, and reduce non-specific bronchial hyperreactivity, and Cromolyn can be used in the research of bronchial asthma. In addition, Cromolyn has multiple activities such as anti-inflammatory, anti-allergic, anti-histamine, anti-cancer, and neuroprotective effects. | ||||||||||||||||||||
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Cromolyn | 99.97% | Cromolyn (Cromoglycate) is an orally active GSK-3β inhibitor with an IC50 of 2.0 μM. Cromolyn is also a mast cell stabilizer that can inhibit the release of mediators from mast cells, regulate reflex bronchoconstriction, and reduce non-specific bronchial hyperreactivity, and Cromolyn can be used in the research of bronchial asthma. In addition, Cromolyn has multiple activities such as anti-inflammatory, anti-allergic, anti-histamine, anti-cancer, and neuroprotective effects. | ||||||||||||||||||||
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Similarity Score 0.85
HY-B0320ACromolyn disodium -
Similarity Score 0.82
HY-W099125RDiethyl 5,5'-((2-hydroxypropane-1,3-diyl)bis(oxy))bis(4-oxo-4H-chromene-2-carboxylate) (Standard) -
Similarity Score 0.75
HY-1290855-Methyl cromolyn disodium -
Similarity Score 0.65
HY-U00148KY-556 -
Similarity Score 0.53
HY-107607FPL-55712 free base -
Similarity Score 0.50
HY-107607AFPL-55712 -
Similarity Score 0.47
HY-172944GPR40 Activator 3 -
Similarity Score 0.47
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HY-N119305-Hydroxy-2-[2-(2-hydroxyphenyl)ethyl]chromone -
Similarity Score 0.47
HY-W8562215,5',5''-(Benzene-1,3,5-triyl)tris(furan-2-carboxylic acid) -
Explore the MedChemAI to find more analogs
![5-Hydroxy-2-[2-(2-hydroxyphenyl)ethyl]chromone Chemical Structure](http://file.medchemexpress.com/product_pic/hy-n11930.gif)
