216571-99-2
Chemical Structure
BODIPY FL Thapsigargin
- CAS No.: 216571-99-2
- Formula:C44H57BF2N2O12
- Molecular Weight:854.74
IUPAC Name: 1-(tert-butyl) 2-methyl (2R,4R)-4-fluoro-2-(methoxymethyl)pyrrolidine-1,2-dicarboxylate
InChIKey: VBVIRSYHHFEDNY-ZXSGOQARSA-N
SMILES: CCCCCCCC(O[C@@H]1[C@@H](OC(/C(C)=C\C)=O)C(C)=C2[C@@]1([H])[C@@](C)(OC(C)=O)C[C@H](OC(CCC3=CC=C(C=C(C(C)=C4)[N]5=C4C)[N-]3[B+3]5([F-])[F-])=O)[C@@]([C@@]6(O)C)(O)[C@@]2([H])OC6=O)=O
Biological Activity: BODIPY FL Thapsigargin is a potent green fluorescent dye. BODIPY FL Thapsigargin inhibits intracellular SERCA-type Ca2+ pumps present in the sarcoplasmic/endoplasmic reticulum. BODIPY FL Thapsigargin used for investigation of thapsigargin binding sites in live cells[1][2].
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BODIPY FL Thapsigargin | BODIPY FL Thapsigargin is a potent green fluorescent dye. BODIPY FL Thapsigargin inhibits intracellular SERCA-type Ca2+ pumps present in the sarcoplasmic/endoplasmic reticulum. BODIPY FL Thapsigargin used for investigation of thapsigargin binding sites in live cells. | |||||||||||||||||||||
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- [1]. Pérez-Gordones MC, et, al. Presence of a thapsigargin-sensitive calcium pump in Trypanosoma evansi: Immunological, physiological, molecular and structural evidences. Exp Parasitol. 2015 Dec;159:107-17. [Content Brief]
- [2]. Urbina DC, et, al. The Ca2+ pump inhibitor, thapsigargin, inhibits root gravitropism in Arabidopsis thaliana. Biol Res. 2006;39(2):289-96. [Content Brief]
Keywords
