2169905-68-2
2169905-68-2
Chemical Structure
Vemtoberant
Synonym(s): APD418
- CAS No.: 2169905-68-2
- Formula:C29H37N3O8S2
- Molecular Weight:619.75
IUPAC Name: bis(5-methylhexyl) phthalate
InChIKey: PVXLIOIISUUKOQ-YADHBBJMSA-N
SMILES: CS(C1=CC=CC(OC[C@@H](O)CN[C@@H]2CC3(OC2)CCN(CC3)S(=O)(C4=CN(CC)C5=CC=CC=C5C4=O)=O)=C1)(=O)=O
Biological Activity: Vemtoberant is a β3-adrenergic receptor inhibitor with a human Ki of 8.2 nM, and exhibits 400- to 600-fold selectivity over human β1-AR and β2-AR. Vemtoberant attenuates β3-AR-mediated cardiac inhibition. Vemtoberant can be used for the research of systolic heart failure[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Vemtoberant | 98.03% | Vemtoberant is a β3-adrenergic receptor inhibitor with a human Ki of 8.2 nM, and exhibits 400- to 600-fold selectivity over human β1-AR and β2-AR. Vemtoberant attenuates β3-AR-mediated cardiac inhibition. Vemtoberant can be used for the research of systolic heart failure. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.95
HY-148804AVemtoberant mesylate -
Similarity Score 0.46
HY-12648AFASN-IN-4 tosylate -
Similarity Score 0.45
HY-12648FASN-IN-4 -
Similarity Score 0.44
HY-118944L-748328 -
Similarity Score 0.44
HY-148402p53 Activator 3 -
Similarity Score 0.43
HY-145933BJJF078 -
Similarity Score 0.43
HY-119229VRT-325 -
Similarity Score 0.43
HY-171006IRF1-IN-1 -
Similarity Score 0.43
HY-1589432-Fluoro QMPSB -
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